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KMID : 0357319750100010019
Journal of the Korean Society for Microbiology
1975 Volume.10 No. 1 p.19 ~ p.24
Isoation of Anaerobic Bacteria form Clinical Specimens



Abstract
Anaerobic bacteria are the major residents of human skin and mucous membrane. The importance, as opportunistic pathogens, of anaerobic bacteria are well recognized because of more population with¢¥ decreased defense against bacterial invasion due to chemotherapy, radiation therapy, extensive surgical operation etc. are dealt at hospitals.
An analysis of the anaerobe isolation¢¥ result¢¥s at Yonsei University Medical Center during the January 1974-May 1975 period¢¥ was made and the following results we¢¥re obtained.
1) From 118 patients 146 strains of anaerobes were isolated. Among these 81 3% were nonsporforming anaerobes. Most frequently isolated anaerobes were Pc. asaccharolyticus, Ps. anaerobius, Ps. intermedius, B. fragilis and Cl. perfringens.
2) Anaerobes were frequently isolated` from wound, female" genital; intraalidominal, and pleuropulmonary specimens. Fewer anaerobes were isolated from¢¥ blood, spinal fluid` and¢¥ liver specimens.
3) The ratio of anaerobe isolation to total bacteria isolation` we¢¥re; liver¢¥ 66.7%, intraabdominal 33.3%, pleuropulmonary 28.9%, spinal fluid 5. 0% and¢¥ blood- 4: 2%.
4) Among the 118 anaerobe isolated patients, 48.3% yielded anaerobes only and rest of them yielded anaerobes together with aerobes.
5) Most of the gram-positive anaerobes were susceptible to¢¥ the antibiotics tested. Exception was to` tetracycline to which appreciable number showed resistance: It was noteworthy that only 48% of B. fragilis was susceptible to tetracycline.
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